For High Precision and Reproducible Kinetic Characterization and Custom Quantitation

• QC-tested to limit biotinylated ligand loading variance, providing lot-to-lot biosensor consistency

• Minimal lot-to-lot biosensor variance enables confident detection of variance from samples

• Rapid and stable capture of biotinylated molecules

Streptavidin-coated surfaces are widely used as a simple and straightforward method of molecular immobilization. Utilized with Bio-Layer Interferometry (BLI), Streptavidin biosensors enable quick and easy modification and customization of the biosensor with any biotin-tagged molecule for quantitative and kinetic measurements. The Dip and Read™ High Precision Streptavidin Biosensor 2.0 (SAX2) is specifically developed and qualified for applications in downstream drug discovery and regulated environments that have stringent assay precision requirements.

SAX2 biosensors are QC-tested at Sartorius to meet our precision-controlled lot-to-lot coefficient of variation (CV) specification of <20% for binding of biotin-tagged molecule onto the biosensor. Within lot, SAX2 biosensors are QC-tested to meet CV of <4%.

SAX2 is designed and optimized for applications that require minimal variation from consumables, to allow for accurate measurements of variance from samples. SAX2 is best suited for:

• Product release QC

• Activity assays in manufacturing

• Highly precise titer determination